If you continue browsing the site, you agree to the use of cookies on this website. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. But if the amount of acid is increased or the amount of mucus is decreased, you could develop an ulcer. Both types are referred to as peptic ulcers. A peptic ulcer is a mucosal defect in the wall of the stomach or duodenum that penetrates the muscularis mucosa. Tehran University of Medical Sciences Ulcers: breaks in the mucosal surface >5 mm, with depth to the submucosa Health care costs of ~$10 billion / year in the US; Despite the constant attack on the gastroduodenal mucosa by noxious agents (acid, pepsin, bile acids, pancreatic enzymes, drugs, and … As for symptomatic presentation of peptic ulcer (Figure 1), stomach pain was the most frequently recorded symptom (88.4%) followed by hyperacidity (60.6%), underweight (57.4%), vomiting (40.6%), loss of appetite (39.4%) while vomiting of blood was found to be least frequent (7.7%). The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Faculty of Pharmacy, Ulcers damage the mucosa of the alimentary tract, which extends through the muscularis mucosa into the sub mucosa or deeper. Antiulcer pharmacology. Peptic ulcer disease (PUD) occurs most commonly in duodenal bulb (duodenal ulcer, DU) and stomach (gastric ulcer, GU). Title: Peptic Ulcer Disease: 1 Peptic Ulcer Disease. Dordrecht, Kluwer Academic Publishers, 1991, pp 273–282. Epidemiology. Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)The most common causes of peptic ulcers are infection with the b… You then may need to undergo diagnostic tests, such as: 1. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Approximately 500,000 new cases are reported each year, with 5 million people affected in the United States alone. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. Background: A prospective study was performed in order to assess the clinical presentation of peptic ulcer. Complications and treatment. See our User Agreement and Privacy Policy. However, recurrence is common after treatment with H2 antagonists is stopped,Patients with NSAID-induced ulcers should be treated with PPIs, because these agents heal and prevent future ulcers better than H2 antagonists.Acute stress ulcers: These drugs are useful in managing acute … This can be confirmed with biopsies obtained at endoscopy and urea breath test, the combination of the two resulting in a detection rate of close to 100… Epidemiology • Peptic ulcers are common and it has been estimated that up to 10% of the population has an ulcer and annual incidence of symptomatic peptic ulcer about 0.3%. Obtaining a medical history, especially for peptic ulcer disease, H pylori infection, ingestion of nonsteroidal anti-inflammatory drugs (NSAIDs), or smoking, is essential in making the correct diagnosis. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . Epidemiology. The pain starts in the epigastrium but by the time of presentation in the emergency department, it is generalized and associated with diffuse peritonitis. Peptic ulcers: All four agents are equally effective in promoting healing of duodenal and gastric ulcers. ulcers. Barnard ; Dept. -… Log in Upload File. When it occurs in stomach its gastric ulcer. The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. 2 Offer lifestyle advice, including advice on healthy eating, weight reduction and smoking cessation, promoting continued use of antacid/alginates. Peptic Ulcer • An Ulcer is … Erosion in the lining of the stomach or the first part of the small intestine, an area called the duodenum. Title: Peptic Ulcer Disease 1 Peptic Ulcer Disease . PDF | On May 30, 2019, Monjur Ahmed published Peptic Ulcer Disease | Find, read and cite all the research you need on ResearchGate Despite the popular belief that peptic ulcers are caused by spicy foods or stress, the reality is that most of the time, peptic ulcers are caused by infection with a bacterium called Helicobacter pylori or use of NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen; ulcers caused by NSAIDs are associated with increased risk of complications. Post on 13-Nov-2014. Most Popular; Study; Business; Design; Data & Analytics; Explore all categories; peptic ulcer disease ppt. If you continue browsing the site, you agree to the use of cookies on this website. Ulcers that form in the stomach are called gastric ulcers; in the duodenum, they are called duodenal ulcers. - Blood supply. Table 2 illustrates data regarding peptic ulcer. It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . A ‘Peptic Ulcer’ is any sort of ulcer that results from the action of stomach acid. Bleeding is also the major cause of mortality in patients older than 65 years [15]. Now customize the name of a clipboard to store your clips. ; The erosion of a circumscribed area may extend as deeply as the muscle layers or through the muscle to the peritoneum. It is possible to get an ulcer almost anywhere. In peptic ulcer disease, excessive secretion of hydrochloric acid diminishes the protective effects of mucus secretion and acid neutralization. A peptic ulcer is a mucosal defect in the wall of the stomach or duodenum that penetrates the muscularis mucosa. In order to detect an ulcer, your doctor may first take a medical history and perform a physical exam. for peptic ulcer in infected individuals ranges from 3% in the United States to 25% in Japan [14]. Document presentation format: On-screen Show (4:3) Company: org Other titles: Arial Wingdings Times New Roman Network 1_Network 2_Network 3_Network 4_Network 5_Network 6_Network 7_Network 8_Network 9_Network 10_Network 11_Network Peptic Ulcer Disease Definition Peptic Ulcers: Gastric & Dudodenal PUD Demographics Comparing Duodenal and Gastric Ulcers Duodenal Ulcers Gastric Ulcers … Barnard ; Dept. Chronic symptoms include ulcer perforation and stricture formation. Dr. J.H. Title: Peptic Ulcer Disease: 1 Peptic Ulcer Disease. Peptic Ulcer Disease: Introduction Peptic ulcer disease represents a serious medical problem. He or she may look for H. pylori using a blood, stool or breath test. Often, they can tell you the exact timeof the perforation. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Precautions. Looks like you’ve clipped this slide to already. 3. Definition: Peptic ulcer is a hole or open sore in the lining of the stomach, duodenum (beginning of the small intestine) or oesophagus. 2. Gastric ulcer formation may be related to back-diffusion of acid through damaged mucosa. Raika Jamali M.D. Free + Easy to edit + Professional + Lots backgrounds. PEPTIC ULCER Types. Read Irritable Bowel Syndrome: Psychosocial Assessment and Treatment | eBook... No public clipboards found for this slide. of Surgery; 2 Historical Aspects. [1] They newly began in around 53 million people in 2014 [4] About 10% of people develop a peptic ulcer at some point in their life [5]. The clinical presentation, diagnosis, treatment for gastric vs. duodenal ulcers are different. The acid can create a painful open sore that may bleed. Complications and treatment. Ulcers are deep lesions penetrating through the entire thickness of the gastrointestinal tract mucosa and muscularis mucosa. AIMST University, Malaysia. Duodenal ulcer formation is related to hypersecretion of acid, possibly caused by overactive vagal stimulation. Carrie Jones; 2 Definition. Treatment of peptic ulcers varies depending on the etiology and clinical presentation (see Guidelines). Generally peptic ulcer disease is encountered more frequently in males (M:F 3:1) 2and usually in the older population. In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. Aims: Definition of peptic ulcer. PEPTIC ULCER DISEASE (Acid – pepsin ulcer disease) G JUMBI SURGICAL ANATOMY • ANATOMY (Stomach and duodenum) -gross anatomy. Drugs: NSAI, Aspirin, cortisone and cytotoxic drugs.. Cigarette smoking. In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. Increased gastric acid secretion. Clipping is a handy way to collect important slides you want to go back to later. A peptic ulcer is an excavation that forms in the mucosal wall of the stomach, in the pylorus, in the duodenum, or in the esophagus. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Peptic ulcers have characteristic symptom of dull, continuous, throbbing pain before meal time or sharp, shooting pain experienced while consuming meals … presentation of perforated peptic ulcer Patients with perforated PUD usually present with an acute onset of abdominal pain. Epidemiology of peptic ulcer. - Microscopic anatomy. Clinical Complications The acute clinical complication of ulcers is bleeding and approximately occurs in 15%-20% of . Etiology and pathophysiology of peptic ulcer. See our Privacy Policy and User Agreement for details. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. 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